5. PREFACE. Exposure Sources of Vinyl Chloride. Acute (short-term) exposure to high levels of vinyl chloride in air has resulted in central nervous system (CNS) effects, such as … (1,2) Under the authority of the Federal Advisory Committee Act (FACA) P.L. References: cancer.gov, OSHA, IARC, CDC If vinyl chloride is detected in your water, contact your local or state health department. Vinyl chloride … Vinyl chloride is a synthetic, colorless gas. It burns easily. Vinyl Chloride 75-01-4 _____ Hazard Summary . This fact sheet discusses possible health risks from exposure to low levels of vinyl chloride typically found in drinking water wells. September 2015 Vinyl Chloride What is vinyl chloride? Occupational exposure to vinyl chloride may occur in those workers concerned with the production, use, transport, storage, and disposal of the chemical. Vinyl chloride is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. The U.S. Environmental Protection Agency has set a maximum contaminant level of 2 ppb of vinyl chloride for public drinking water supplies. Acute Exposure Guideline Levels. Most vinyl chloride is used to make polyvinyl chloride (PVC) plastic and vinyl products. Angiosarcoma attacks the lining of blood vessels, and can occur in any area of the body. Prolonged exposure can cause cancer in the liver, brain, blood and lungs. Vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer called angiosarcoma. Studies in workers who inhale vinyl chloride over many years show an increased risk of … In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though o … Primary exposure to vinyl chloride occurs through inhalation. Final AEGLs for Vinyl chloride (75-01-4) Exposure Period AEGL-1 AEGL-2 AEGL-3; 10 minutes: 450 ppm : 2800 ppm : 12000 ppm : 30 minutes: 310 ppm : 1600 ppm : 6800 ppm : 60 minutes: 250 ppm : 1200 ppm : 4800 ppm : 4 hours: 140 ppm : 820 ppm : 3400 ppm : 8 hours: 70 ppm : 820 ppm : 3400 ppm Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. Vinyl Chloride 1. Polyvinyl chloride, also known as PVC or vinyl, is arguably one of the most toxic types of plastic in our lives. Do standards exist for exposure to vinyl chloride? A statement of each employee's suitability for continued exposure to vinyl chloride including use of protective equipment and respirators, shall be obtained from the examining physician promptly after any examination. It is not stable at high temperatures. Sloane K. Tilley, Rebecca C. Fry, in Systems Biology in Toxicology and Environmental Health, 2015. 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